{"id":6170,"date":"2022-03-09T07:30:00","date_gmt":"2022-03-09T07:30:00","guid":{"rendered":"https:\/\/realheart.se\/mfn_news\/artificial-organs-publishes-libera-fresiellos-research\/"},"modified":"2022-03-09T07:30:00","modified_gmt":"2022-03-09T07:30:00","slug":"artificial-organs-publishes-libera-fresiellos-research","status":"publish","type":"mfn_news","link":"https:\/\/realheart.se\/sv\/mfn_news\/artificial-organs-publishes-libera-fresiellos-research\/","title":{"rendered":"Artificial Organs publishes Libera Fresiello’s research"},"content":{"rendered":"
Press release, 09 March 2022
\nRealheart is collaborating with a number of international researchers to develop the world's first four-chamber artificial heart. One is Professor Libera Fresiello at Katholieke Universiteit Leuven and University of Twente. The results of her study of the Realheart TAH in a hybrid simulator has now been published by the journal Artificial Organs.<\/strong><\/div>\n

Professor Libera Fresiello has conducted tests of the previous version Realheart TAH (Total Artificial Heart) in a hybrid simulator \u2013 a digital model of the human heart, lungs and blood vessels, to which the artificial heart is connected to study its interaction with the body in a variety of scenarios. This information was used to further improve the design of the clinical version currently in production.<\/span><\/span><\/span><\/span><\/p>\n

''Developing a total artificial heart is a major challenge from both an engineering and a clinical point of view. It must interact safely and effectively with the human vascular system, providing the right support to organs and tissues. By studying it in a simulated environment, we can predict how it would behave in a real human body. I believe this type of methodology will be used more and more as a complement or alternative to animal testing in the future,'' said Professor Libera Fresiello. <\/span><\/span><\/span><\/span><\/p>\n

One reason limiting the use of artificial hearts is that the products that have been available often lead to for example blood-related complications. This is why Realheart is focusing on creating an artificial heart that mimics the way the natural heart supplies blood to the body's organs in a pulsating flow. <\/span><\/span><\/span><\/span><\/p>\n

Prof Fresiello's studies show that the Realheart TAH produces such a pulsatile blood flow, which can be adjusted by stroke volume and pulse rate. The two artificial ventricles work independently and if controlled properly, they can attain a right-left balance. <\/span><\/span><\/span><\/span><\/p>\n

''This is exactly what we aim to achieve. This research will therefore be of great importance in our work. The fact that it is now also presented in a scientific journal such as Artificial Organs will further contribute to greater awareness, trust, and interest in our artificial heart, which is very positive,'' said Ina Laura Perkins, CEO of Realheart.<\/span><\/span><\/span><\/span><\/p>\n

Artificial Organs is a peer-reviewed biomedical journal covering organ replacement technology. The journal was founded in 1977 and is published monthly. Dr Fresiello's article ''Hemodynamic characterization of the Realheart total artificial heart with a hybrid cardiovascular simulator'' will be published in the next printed issue and has already been published online. <\/span><\/span><\/span><\/span><\/p>\n

https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/aor.14223<\/span><\/span><\/span><\/span><\/p>\n

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For more information please contact:<\/span><\/span><\/strong><\/span><\/p>\n

Ina Laura Perkins, CEO<\/span><\/span><\/p>\n

Phone: +46(0)70 406 49 21\u00a0<\/span><\/span><\/p>\n

E-mail: inalaura.perkins@realheart.se<\/span><\/span><\/p>\n

Certified Adviser: Svensk Kapitalmarknadsgranskning AB, Phone: +46 11 32 30\u00a0732, email:\u00a0ca@skmg.se<\/a><\/p>\n<\/div>\n

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Scandinavian Real Heart AB develops a total artificial heart (TAH) for implantation in patients with life-threatening heart failure. Realheart TAH has a unique, patented design that resembles that of the natural human heart. The artificial heart consists of a four-chamber system (two atriums and two chambers) which provides the opportunity to generate a physiologically adapted blood flow that mimics the body's natural circulation. A unique concept in the medical technology world.<\/span><\/em><\/span><\/span><\/span><\/p>\n<\/div>\n